Paper
3 December 2021 Investigating changes in skin biochemistry due to discoid lupus erythematosus using Raman spectroscopy and mass spectrometry
Hannah U. Holtkamp, Federico Marini, Liam Quinn, Claude Aguergaray, Michel Nieuwoudt, Gus Grey, Paul Jarrett, Cather Simpson
Author Affiliations +
Abstract
Discoid Lupus Erythematosus is a dermatological disease difficult to diagnose. By using Raman spectroscopy and MALDI mass spectrometry a shift in lipid biochemistry has been identified relative to healthy tissue, that can improve early detection.
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Hannah U. Holtkamp, Federico Marini, Liam Quinn, Claude Aguergaray, Michel Nieuwoudt, Gus Grey, Paul Jarrett, and Cather Simpson "Investigating changes in skin biochemistry due to discoid lupus erythematosus using Raman spectroscopy and mass spectrometry", Proc. SPIE 11921, Emerging Technologies for Cell and Tissue Characterization, 119210I (3 December 2021); https://doi.org/10.1117/12.2615636
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KEYWORDS
Raman spectroscopy

Skin

Biochemistry

Mass spectrometry

Analytical research

Principal component analysis

Tissues

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