Non-invasive coronary CT angiography identification of thin-cap fibroatheroma determined by intravascular optical coherence tomography

Justin Kim; Juhwan Lee; Lia Gomez-Perez; Vladislav N. Zimin; Mohamed H. Makhlouf; Sadeer Al-Kindi; David L. Wilson

doi:10.1117/12.2653220

10 April 2023 Non-invasive coronary CT angiography identification of thin-cap fibroatheroma determined by intravascular optical coherence tomography

Justin Kim, Juhwan Lee, Lia Gomez-Perez, Vladislav N. Zimin, Mohamed H. Makhlouf, Sadeer Al-Kindi, David L. Wilson

Author Affiliations +

Proceedings Volume 12468, Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging; 124680S (2023) https://doi.org/10.1117/12.2653220
Event: SPIE Medical Imaging, 2023, San Diego, California, United States

Abstract

This study aimed to determine the potential of pericoronary adipose tissue (PCAT) radiomics in non-invasively identifying thin cap fibroatheroma (TCFA) in coronary CTA images. TCFA is a precursor of plaque rupture and can only be visualized using intravascular OCT (IVOCT). Our findings showed that PCAT radiomics can be used to identify TCFA as assessed by IVOCT, potentially improving the accuracy of risk assessment and treatment planning. This is the first study to demonstrate the use of PCAT radiomics for non-invasive identification of TCFA.

Conference Presentation

Citation Download Citation

Justin Kim, Juhwan Lee, Lia Gomez-Perez, Vladislav N. Zimin, Mohamed H. Makhlouf, Sadeer Al-Kindi, and David L. Wilson "Non-invasive coronary CT angiography identification of thin-cap fibroatheroma determined by intravascular optical coherence tomography", Proc. SPIE 12468, Medical Imaging 2023: Biomedical Applications in Molecular, Structural, and Functional Imaging, 124680S (10 April 2023); https://doi.org/10.1117/12.2653220

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