Optical coherence tomography-measured blood vessel characteristics within and between port-wine birthmarks

Rachel Elsanadi; Feben Messele; Kristen M. Kelly

doi:10.1117/12.3003200

12 March 2024 Optical coherence tomography-measured blood vessel characteristics within and between port-wine birthmarks

Rachel Elsanadi, Feben Messele, Kristen M. Kelly

Author Affiliations +

Proceedings Volume 12816, Photonics in Dermatology and Plastic Surgery 2024; 1281603 (2024) https://doi.org/10.1117/12.3003200
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Port-Wine Birthmarks (PWB) are vascular birthmarks occurring in 0.3-0.5% of the population.1 First-line treatment is pulsed-dye laser (PDL), however, there is rarely full clearance of lesions. Dynamic-OCT (D-OCT) was used to measure blood vessel density (%) and diameter (micrometers) in the dermis of single PWBs at depths between 0.15mm and 0.5mm. Average ratios of vessel density and diameter in affected compared to control skin were obtained for each PWB by averaging data for all spots within a lesion. Density was consistently greater in affected skin compared to control skin at deeper depths in hypertrophic lesions than in flat lesions. Diameter did not vary consistently with depth. In conclusion, there is a great deal of variability in OCT-measured vessel density and diameter within and between PWBs. OCT provides data on individual lesion characteristics that could potentially be used for laser treatment planning.

Conference Presentation

Citation Download Citation

Rachel Elsanadi, Feben Messele, and Kristen M. Kelly "Optical coherence tomography-measured blood vessel characteristics within and between port-wine birthmarks", Proc. SPIE 12816, Photonics in Dermatology and Plastic Surgery 2024, 1281603 (12 March 2024); https://doi.org/10.1117/12.3003200

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