Exploring optoretinographic responses of photoreceptor function in disease-affected retinas

Reddikumar Maddipatla; Christopher S. Langlo; Kari V. Vienola; Maciej M. Bartuzel; Ewelina Pijewska; Robert J. Zawadzki; Ravi S. Jonnal

doi:10.1117/12.3003007

12 March 2024 Exploring optoretinographic responses of photoreceptor function in disease-affected retinas

Reddikumar Maddipatla, Christopher S. Langlo, Kari V. Vienola, Maciej M. Bartuzel, Ewelina Pijewska, Robert J. Zawadzki, Ravi S. Jonnal

Author Affiliations +

Proceedings Volume 12824, Ophthalmic Technologies XXXIV; 1282406 (2024) https://doi.org/10.1117/12.3003007
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Assessment of the functional response of photoreceptors plays an important role in assessing and treating vision loss. Optoretinography (ORG) is an emerging non-invasive technique that measures the photoreceptors’ functional response to external light stimuli using optical coherence tomography (OCT) or other phase-sensitive imaging modalities. Recently a novel velocity-based ORG method was demonstrated, illustrating the feasibility of measuring photoreceptor function with clinical-grade OCT systems. Here we test this technique on diseaseaffected retinae of human subjects. The disease-affected retinae exhibited altered responses when compared to a healthy volunteer. The findings indicate promise for this novel tool to find applications in the clinic and clinical research.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Reddikumar Maddipatla, Christopher S. Langlo, Kari V. Vienola, Maciej M. Bartuzel, Ewelina Pijewska, Robert J. Zawadzki, and Ravi S. Jonnal "Exploring optoretinographic responses of photoreceptor function in disease-affected retinas", Proc. SPIE 12824, Ophthalmic Technologies XXXIV, 1282406 (12 March 2024); https://doi.org/10.1117/12.3003007

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