Development of a multimodal optical system for quantitative biological tissue characterization

Inyoung Park; Seonghui Im; Jonghee Yoon

doi:10.1117/12.3018206

26 February 2024 Development of a multimodal optical system for quantitative biological tissue characterization

Inyoung Park, Seonghui Im, Jonghee Yoon

Proceedings Volume 13076, SPIE Advanced Biophotonics Conference (SPIE ABC 2023); 1307606 (2024) https://doi.org/10.1117/12.3018206
Event: SPIE Advanced Biophotonics Conference (SPIE ABC 2023), 2023, Jeju, Korea, Republic of

Abstract

Rapid and accurate disease diagnosis is important to determine appropriate treatment methods in clinics. Optical properties of tissue, such as absorption and scattering coefficients, could be a useful marker as disease progression occurs structural and biochemical alterations of biological tissue, resulting in chances of its optical properties. In addition, optical imaging methods are usually cost-effective and safe compared to other medical imaging techniques; thus, optical imaging could be used as a versatile tool for disease diagnosis. In this study, we have developed a multimodal imaging system that combines hyperspectral imaging and spatial-frequency domain imaging techniques. The proposed optical system enables quantitative measurement of scattering and absorption coefficients in biological tissue. We demonstrated the capability of the proposed optical system in measuring optical properties by exploiting a tissue-mimicking phantom and color chart, indicating that it has potential as a useful tool for characterizing the optical properties of tissue.

Citation Download Citation

Inyoung Park, Seonghui Im, and Jonghee Yoon "Development of a multimodal optical system for quantitative biological tissue characterization", Proc. SPIE 13076, SPIE Advanced Biophotonics Conference (SPIE ABC 2023), 1307606 (26 February 2024); https://doi.org/10.1117/12.3018206

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available