Capabilities of photon-counting systems and possible applications in biomedicine

Jonathon R. Howorth; Christopher G. Morgan

doi:10.1117/12.146720

24 June 1993 Capabilities of photon-counting systems and possible applications in biomedicine

Jonathon R. Howorth, Christopher G. Morgan

Proceedings Volume 1895, Ultrasensitive Laboratory Diagnostics; (1993) https://doi.org/10.1117/12.146720
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

The continued development of the vacuum tube results in image intensifiers with ever increasing capabilities in spatial resolution, and time resolution. Detectors with resolution exceeding 3000 X 2000 pixels have been developed for ground base astronomy, and space telescopes, where the extreme sensitivity in the visible, UV, X-, and Gamma parts of the spectrum are of primary consideration. Such detectors are now finding applications in biomedicine. In particular beta-labelled autoradiography and fluorescent imaging of sensitive samples at very high resolution with very low stimulation are possible. The time resolution of the detectors can be exploited in new areas such as fluorescent lifetime imaging and transillumination of tissues. It is confidently expected that the new detectors will find many more applications and this paper is an attempt to stimulate discussion.

Citation Download Citation

Jonathon R. Howorth and Christopher G. Morgan "Capabilities of photon-counting systems and possible applications in biomedicine", Proc. SPIE 1895, Ultrasensitive Laboratory Diagnostics, (24 June 1993); https://doi.org/10.1117/12.146720

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