Fluorescence spectroscopy of normal and cancerous human stomach tissue

Maria L. Fraser Monteiro; T. Rezio; Jorge Soares; J. M.G. Martinho; Dawei Liang; Luis Fraser Monteiro

doi:10.1117/12.166832

15 January 1994 Fluorescence spectroscopy of normal and cancerous human stomach tissue

Maria L. Fraser Monteiro, T. Rezio, Jorge Soares, J. M.G. Martinho, Dawei Liang, Luis Fraser Monteiro

Proceedings Volume 2081, Optical Biopsy; (1994) https://doi.org/10.1117/12.166832
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

The autofluorescence of cancerous and normal human stomach tissues was measured in vitro, by fluorescence spectroscopy, within three hours of surgery ablation. A new fluorescence emission band, centered at about 380 nm for the cancerous stomach tissue is reported, for 340 nm excitation. This band is practically absent for the normal tissue when this is excited at the same wavelength. For UVB excitation (between 283 and 305 nm) the emission bands are centered around 350 nm and 470 nm, for both tissues, in agreement with the literature. The ratios of the fluorescence intensities for cancerous and normal tissues are measured at the center of the three bands, the intensity for the diseased tissue being always higher than for the normal one. The presence of a new band centered at 380 nm, combined with the intensity ratios, may prove of great relevance towards early in vivo detection of stomach cancer.

Citation Download Citation

Maria L. Fraser Monteiro, T. Rezio, Jorge Soares, J. M.G. Martinho, Dawei Liang, and Luis Fraser Monteiro "Fluorescence spectroscopy of normal and cancerous human stomach tissue", Proc. SPIE 2081, Optical Biopsy, (15 January 1994); https://doi.org/10.1117/12.166832

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