Holmium:YAG laser effects on articular cartilage metabolism: in vitro

R. Lane Smith; L. Montgomery M.D.; G. Fanton M.D.; M. Dillingham M.D.; D. J. Schurman M.D.

doi:10.1117/12.184892

7 September 1994 Holmium:YAG laser effects on articular cartilage metabolism: in vitro

R. Lane Smith, L. Montgomery M.D., G. Fanton M.D., M. Dillingham M.D., D. J. Schurman M.D.

Proceedings Volume 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV; (1994) https://doi.org/10.1117/12.184892
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

We report effects of applying variable doses of Holmium:YAG laser energy to bovine articular cartilage in vitro. The response of the cartilage to the Holmium:YAG laser energy was determined by quantification of cell proliferation and extracellular matrix glycosaminoglycan synthesis. This study demonstrates that articular cartilage cell metabolism was maintained at a normal level following treatment of cartilage at a dose of 0.6 joules/pulse. The laser energy was applied at 10 Hz for 10 seconds at 1 mm distance from the cartilage. Under these conditions and at a dose of 0.6 joules/pulse, the total energy density was calculated to be 240 joules/cm², assuming minimal loss of energy due to water absorption. Energy levels grater than 0.8 joules/pulse corresponding to calculated energy densities greater than 320 joules/cm² proved harmful to cartilage. Our data demonstrate that low levels of Holmium:YAG laser energy can be applied to articular cartilage under conditions that maintain and/or stimulate cell metabolism.

Citation Download Citation

R. Lane Smith, L. Montgomery M.D., G. Fanton M.D., M. Dillingham M.D., and D. J. Schurman M.D. "Holmium:YAG laser effects on articular cartilage metabolism: in vitro", Proc. SPIE 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV, (7 September 1994); https://doi.org/10.1117/12.184892

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