Surface plasmon resonance biosensor miniaturization

Mark W. Foster; Douglas J. Ferrell; Robert A. Lieberman

doi:10.1117/12.190962

21 October 1994 Surface plasmon resonance biosensor miniaturization

Mark W. Foster, Douglas J. Ferrell, Robert A. Lieberman

Proceedings Volume 2293, Chemical, Biochemical, and Environmental Fiber Sensors VI; (1994) https://doi.org/10.1117/12.190962
Event: SPIE's 1994 International Symposium on Optics, Imaging, and Instrumentation, 1994, San Diego, CA, United States

Abstract

Surface plasmon resonance (SPR) biosensing promises a sensitive technique for the rapid quantization of a variety of analytes of interest to environmental sensing, chem/biological warfare detection, and medical screening. For many applications a compact, handheld sensor would be advantageous, however present implementations are not well suited to miniaturization. Using a substrate mode waveguide to excite SPR, a miniaturized SPR system has been demonstrated that is small enough to fit in the palm of a users hand. Preliminary testing has demonstrated 7 nanomolar sensitivity for an immunoassay biosensor.

Citation Download Citation

Mark W. Foster, Douglas J. Ferrell, and Robert A. Lieberman "Surface plasmon resonance biosensor miniaturization", Proc. SPIE 2293, Chemical, Biochemical, and Environmental Fiber Sensors VI, (21 October 1994); https://doi.org/10.1117/12.190962

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