Investigation of laser Doppler techniques using the Monte Carlo method

Walter Ruetten; Thomas Gellekum; Katrin Jessen

doi:10.1117/12.200830

31 January 1995 Investigation of laser Doppler techniques using the Monte Carlo method

Walter Ruetten, Thomas Gellekum, Katrin Jessen

Proceedings Volume 2326, Photon Transport in Highly Scattering Tissue; (1995) https://doi.org/10.1117/12.200830
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

Laser Doppler techniques are increasingly used in research and clinical applications to study perfusion phenomena in the skin, yet the influences of changing scattering parameters and geometry on the measure of perfusion are not well explored. To investigate these influences, a simulation program based on the Monte Carlo method was developed, which is capable of determining the Doppler spectra caused by moving red blood cells. The simulation model allows for the definition of arbitrary networks of blood vessels with individual velocities. The volume is represented by a voxel tree with adaptive spatial resolution which contains references to the optical properties and is used to store the location dependent photon fluence determined during the simulation. Two evaluation methods for Doppler spectra from biological tissue described in the literate were investigated with the simulation program. The results obtained suggest that both methods give a measure of perfusion nearly proportional to the velocity of the red blood cells. However, simulations done with different geometries of the blood vessels seem to indicate a nonlinear behavior concerning the concentration of red blood cells in the measurement volume. Nevertheless these simulation results may help in the interpretation of measurements obtained from devices using the investigated evaluation methods.

Citation Download Citation

Walter Ruetten, Thomas Gellekum, and Katrin Jessen "Investigation of laser Doppler techniques using the Monte Carlo method", Proc. SPIE 2326, Photon Transport in Highly Scattering Tissue, (31 January 1995); https://doi.org/10.1117/12.200830

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