Investigation of multilayered tissue with in vivo reflectance measurements

Alwin Kienle; Lothar D. Lilge; Michael S. Patterson; Brian C. Wilson; Raimund Hibst; Rudolf W. Steiner

doi:10.1117/12.200824

31 January 1995 Investigation of multilayered tissue with in vivo reflectance measurements

Alwin Kienle, Lothar D. Lilge, Michael S. Patterson, Brian C. Wilson, Raimund Hibst, Rudolf W. Steiner

Proceedings Volume 2326, Photon Transport in Highly Scattering Tissue; (1995) https://doi.org/10.1117/12.200824
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

Light propagation in multi-layered tissues was studied theoretically and experimentally on a rabbit thigh and on human forearms. Theoretical investigations were based on a special solution of the diffusion equation considering layered materials or on Monte Carlo simulations. The spatially resolved reflectance of a small diameter laser beam (633 or 751 nm) incident on the tissue was measured in vivo with a CCD-camera based system previously tested with homogeneous tissue simulating phantoms. The optical coefficients were determined either by non-linear regressions to a solution of the diffusion equation or to Monte Carlo simulations. We fitted up to four independent parameters to describe the spatially resolved reflectance from two- and three-layered tissues.

Citation Download Citation

Alwin Kienle, Lothar D. Lilge, Michael S. Patterson, Brian C. Wilson, Raimund Hibst, and Rudolf W. Steiner "Investigation of multilayered tissue with in vivo reflectance measurements", Proc. SPIE 2326, Photon Transport in Highly Scattering Tissue, (31 January 1995); https://doi.org/10.1117/12.200824

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