Dynamic area telethermometry and its clinical applications

Michael Anbar

doi:10.1117/12.204868

28 March 1995 Dynamic area telethermometry and its clinical applications

Michael Anbar

Proceedings Volume 2473, Thermosense XVII: An International Conference on Thermal Sensing and Imaging Diagnostic Applications; (1995) https://doi.org/10.1117/12.204868
Event: SPIE's 1995 Symposium on OE/Aerospace Sensing and Dual Use Photonics, 1995, Orlando, FL, United States

Abstract

Dynamic area telethermometry (DAT) is a recent development in thermology, the science of biological heat generation and dissipation. DAT is based on monitoring changes in infrared emission, deriving from them information on the kinetics and mechanisms of biological thermoregulation. Remotely monitoring infrared emission is the most reliable technique to study bioenergetics, because it minimally perturbs the investigated system. Area monitoring of heat dissipating surfaces is needed because temporal changes in the spatial distribution of temperature conveys information on mechanisms of thermoregulation. DAT can be applied to biological systems ranging from single cells (microtelecalorimetry) to large areas of human skin (clinical thermology). DAT requires the accumulation of many (hundreds to thousands) thermal images followed by analysis of the thermokinetics of each pixel or group of pixels. In clinical thermology this analysis uses FFT to extract systemic, regional and local thermoregulatory frequencies (TRFs). DAT also extracts information on local thermoregulation from the temporal behavior of homogeneity of skin temperature (HST). Analysis of the relative contributions (FFT amplitudes) of the different frequencies allows distinction between vascular, neurological, and immunological thermoregulatory dysfunctions. This analysis, which can reveal the mechanism of the dysfunction, can be very useful in the diagnosis and staging of various disorders, ranging from diabetes mellitus and liver cirrhosis to breast cancer and malignant melanoma. From the engineering standpoint DAT requires highly stable imaging systems and effective display of the spatial distribution of TRFs to allow identification of thermoregulatory pathways and their dysfunction.

Citation Download Citation

Michael Anbar "Dynamic area telethermometry and its clinical applications", Proc. SPIE 2473, Thermosense XVII: An International Conference on Thermal Sensing and Imaging Diagnostic Applications, (28 March 1995); https://doi.org/10.1117/12.204868

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