Diffusing temporal light correlation for burn diagnosis

David A. Boas; Goro Nishimura; Arjun G. Yodh

doi:10.1117/12.280281

18 August 1997 Diffusing temporal light correlation for burn diagnosis

David A. Boas, Goro Nishimura, Arjun G. Yodh

Proceedings Volume 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II; (1997) https://doi.org/10.1117/12.280281
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

The non-invasive determination of the depth of severe burns is an important problem whose solution would offer medical practitioners a valuable tool for diagnosing and treating severe burns. Burned tissue is essentially a turbid medium with spatial varying dynamics: light is multiply scattered by the tissue and layers of burned tissue are distinguished by the degree of blood flow. The dynamical properties of turbid media can be probed by monitoring the temporal fluctuations of scattered light speckles. Information on a system's dynamics is obtained from the temporal autocorrelation function of these intensity fluctuations. We have recently shown that the correlation diffusion equation (CDE) accurately predicts the temporal correlation function for turbid systems with spatially varying dynamics and that the dynamical properties of such systems can be imaged using standard reconstruction algorithms. In this contribution, we demonstrate the sensitivity of temporal field correlation measurements to variations of 100 micrometers in burn thickness and the potential applicability of the CDE for quantitation of burn thickness. Results are presented from burn phantoms and pig models. The combination of diffusing temporal light correlation with diffuse reflectometry for enhanced burn diagnosis is investigated.

Citation Download Citation

David A. Boas, Goro Nishimura, and Arjun G. Yodh "Diffusing temporal light correlation for burn diagnosis", Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); https://doi.org/10.1117/12.280281

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