Technique for noninvasive monitoring of blood loss via oxygen saturation measurements in the eye

Matthew H. Smith; Kurt R. Denninghoff; Lloyd W. Hillman; Charles E. Hughes; Thomas E. Minninch; Russell A. Chipman

doi:10.1117/12.273639

2 May 1997 Technique for noninvasive monitoring of blood loss via oxygen saturation measurements in the eye

Matthew H. Smith, Kurt R. Denninghoff, Lloyd W. Hillman, Charles E. Hughes, Thomas E. Minninch, Russell A. Chipman

Proceedings Volume 2982, Optical Diagnostics of Biological Fluids and Advanced Techniques in Analytical Cytology; (1997) https://doi.org/10.1117/12.273639
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

We describe a noninvasive technique and instrumentation for measuring the oxygen saturation of blood in retinal arteries and veins. A white-light image of a subject's retina is presented to an operator. The operator targets a particular retinal artery or vein and initiates the measurement procedure. The measurements are made by scanning low-power lasers into the eye and across the retinal vessel. The light reflected and scattered back out of the eye is collected and measured. The oxygen saturation of blood within the vessel is spectroscopically determined by analyzing the vessel absorption profiles at two or more wavelengths. A complete saturation measurement can be made in less than one second, allowing real-time measurement during physiological changes. The sensitivity of this measurement technique to changes in retinal saturation has been demonstrated through a series of pilot studies in anesthetized swine. We present data indicating that retinal venous oxygen saturation decreases predictably during ongoing blood loss, indicating a potential application of an eye oximeter to nonivasively monitor blood loss. Current invasive techniques for monitoring bleeding, such as fiber optic pulmonary catheters, are not suited for use early in trauma situations. A portable eye oximeter may therefore provide a new technique for reducing mortality in the emergency department setting.

Citation Download Citation

Matthew H. Smith, Kurt R. Denninghoff, Lloyd W. Hillman, Charles E. Hughes, Thomas E. Minninch, and Russell A. Chipman "Technique for noninvasive monitoring of blood loss via oxygen saturation measurements in the eye", Proc. SPIE 2982, Optical Diagnostics of Biological Fluids and Advanced Techniques in Analytical Cytology, (2 May 1997); https://doi.org/10.1117/12.273639

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