Human sclera dynamic spectra: in-vitro and in-vivo measurements

Alexey N. Bashkatov; Valery V. Tuchin; Elina A. Genina; Yurii P. Sinichkin; Nina A. Lakodina; Vyacheslav I. Kochubey

doi:10.1117/12.350592

18 June 1999 Human sclera dynamic spectra: in-vitro and in-vivo measurements

Alexey N. Bashkatov, Valery V. Tuchin, Elina A. Genina, Yurii P. Sinichkin, Nina A. Lakodina, Vyacheslav I. Kochubey

Proceedings Volume 3591, Ophthalmic Technologies IX; (1999) https://doi.org/10.1117/12.350592
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

Experimental results on the optical properties of the human eye sclera controlled by administration of osmotically active chemicals, such as propylene glycol and glucose are presented. Administration of chemical agents induces diffusion of matter and as a result equalization of the refractive indices of collagen and ground material. Experimental study of influence of propylene glycol and glucose on reflectance and transmittance spectra of human eye sclera was performed. In vitro diffusion reflectance spectra of the whole human eye and transmittance spectra of the sclera samples were investigated. In vivo measurements were fulfilled on a rabbit eyes. The significant increase of transmittance and decrease of reflectance of human eye sclera and rabbit eye under action of osmolytic liquids was demonstrated. The matter diffusion coefficient for the scleral samples impregnated by glucose solution was estimated; the average value is 1.27x10^-5 ± 2.26x10^-6 cm²/sec. The results are general and can be used to describe many other fibrous tissues.

Citation Download Citation

Alexey N. Bashkatov, Valery V. Tuchin, Elina A. Genina, Yurii P. Sinichkin, Nina A. Lakodina, and Vyacheslav I. Kochubey "Human sclera dynamic spectra: in-vitro and in-vivo measurements", Proc. SPIE 3591, Ophthalmic Technologies IX, (18 June 1999); https://doi.org/10.1117/12.350592

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