Near-infrared absorption and scattering spectra of tissues in vivo

Maria-Angela Franceschini; Enrico Gratton; Dennis M. Hueber; Sergio Fantini

doi:10.1117/12.356854

15 July 1999 Near-infrared absorption and scattering spectra of tissues in vivo

Maria-Angela Franceschini, Enrico Gratton, Dennis M. Hueber, Sergio Fantini

Proceedings Volume 3597, Optical Tomography and Spectroscopy of Tissue III; (1999) https://doi.org/10.1117/12.356854
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

Tissue inhomogeneity is often neglected in the analysis of the spectral data collected in tissues. We have measured the absorption and reduced scattering spectra of the human forearm in the wavelength range 633-841 nm, and in the range of source-detector separations 0.7-3.3 cm. We found that the layered tissue structure due to the skin and adipose layers may have a significant effect not only on the data collected at different distances, but also on the data at 633 nm, where the optical absorbance is significantly higher than at the longer wavelengths considered. We conclude that the dependence of the optical penetration depth on the absorption and reduced scattering coefficients should be carefully considered in the quantitative analysis of the optical spectra of tissues.

Citation Download Citation

Maria-Angela Franceschini, Enrico Gratton, Dennis M. Hueber, and Sergio Fantini "Near-infrared absorption and scattering spectra of tissues in vivo", Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); https://doi.org/10.1117/12.356854

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