Ex-vivo testing of crystalline lens substitutes: a pilot study

Marie Hamaoui; Jean-Marie A. Parel; Fabrice Manns; Hassan Tahi; Arthur Ho; Brien Holden

doi:10.1117/12.387515

7 June 2000 Ex-vivo testing of crystalline lens substitutes: a pilot study

Marie Hamaoui, Jean-Marie A. Parel, Fabrice Manns, Hassan Tahi, Arthur Ho, Brien Holden

Proceedings Volume 3908, Ophthalmic Technologies X; (2000) https://doi.org/10.1117/12.387515
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

The paper reviews two techniques being developed for ex-vivo testing of crystalline lens substitutes. The techniques may be used to test polymers developed for the Restore Accommodation (RA) project. Harvested rabbit and human lenses were used in preliminary tests to determine the feasibility of topographical analysis of the crystalline lens and ex-vivo cell culturing of the lens capsule. Lens capsules were cultured to test formation of posterior capsule opacification (PCO) in the presence of RA polymers. Feasibility of analyzing lens shape with the PAR^TM Sys Corneal Topography System was determined using whole lenses. Preliminary results indicate that topography and cell culturing of lens capsules may be used to evaluate RA polymers.

Citation Download Citation

Marie Hamaoui, Jean-Marie A. Parel, Fabrice Manns, Hassan Tahi, Arthur Ho, and Brien Holden "Ex-vivo testing of crystalline lens substitutes: a pilot study", Proc. SPIE 3908, Ophthalmic Technologies X, (7 June 2000); https://doi.org/10.1117/12.387515

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KEYWORDS

Eye

Polymers

Cornea

Crystals

In vivo imaging

Microscopes

Eye models

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