Spatial variation of fluorescence in human breast tissues

Asima Pradhan; Maya S. Nair; N. Ghosh; Asha Agarwal

doi:10.1117/12.382733

19 April 2000 Spatial variation of fluorescence in human breast tissues

Asima Pradhan, Maya S. Nair, N. Ghosh, Asha Agarwal

Proceedings Volume 3917, Optical Biopsy III; (2000) https://doi.org/10.1117/12.382733
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

Spatial variation of fluorescence intensity in human breast tissues was studied. A diffusion theory model describing fluorescence light energy distribution inside a thick and turbid medium like human tissue was developed. Experimental data were fitted with the theoretical model to obtain reduced scattering coefficient and absorption coefficient at different fluorescence wavelengths with 488nm excitation of normal, malignant and benign breast tissues. Computed reduced scattering and absorption coefficients of malignant tissues were observed to be more as compared to the normal tissues and benign tumors.

Citation Download Citation

Asima Pradhan, Maya S. Nair, N. Ghosh, and Asha Agarwal "Spatial variation of fluorescence in human breast tissues", Proc. SPIE 3917, Optical Biopsy III, (19 April 2000); https://doi.org/10.1117/12.382733

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