Radiotherapy of malignant tumors using low-intensity laser radiation as a radiosensitizer

Pavel Yu. Polyakov; Oleg A. Bychenkov; N. A. Larionova; Dmitrii A. Rogatkin

doi:10.1117/12.375273

30 December 1999 Radiotherapy of malignant tumors using low-intensity laser radiation as a radiosensitizer

Pavel Yu. Polyakov, Oleg A. Bychenkov, N. A. Larionova, Dmitrii A. Rogatkin

Proceedings Volume 4059, Laser Use in Oncology II; (1999) https://doi.org/10.1117/12.375273
Event: Selected Papers on Laser Use in Oncology II, 1999, none, Armenia

Abstract

A new method of radiosensitization is offered using low- intensity laser radiation (LILR). Theoretic and methodological aspects involved as well as specially developed apparatus are discussed. Radiotherapy combined with LILR was approved in 78 patients with cutaneous and oropharyngeal tumors II-IV. Combined treatment with LILR as a radiosensitizing procedure and subsequent radiotherapy doesn't increase the degree of local reactions in response to radiation, and provide the reliable improvement of the therapy outcome: the total index of significant plus pronounced tumor regression, owing to the radiosensitization, trustworthy rises from 65.7 +/- 5.8% to 84.3 +/- 4.3% (t equals 2.58; p < 0.05), the three-year survival index--from 44.6 +/- 5.5% up to 60.3 +/- 5.5% (t equals 2.02; p < 0.05).

Citation Download Citation

Pavel Yu. Polyakov, Oleg A. Bychenkov, N. A. Larionova, and Dmitrii A. Rogatkin "Radiotherapy of malignant tumors using low-intensity laser radiation as a radiosensitizer", Proc. SPIE 4059, Laser Use in Oncology II, (30 December 1999); https://doi.org/10.1117/12.375273

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