Novel photosensitizers for prospective clinical usage and some of their properties

Andrei V. Reshetnickov; Stefan B. Spaniol; N. P. Neugodova; G. A. Sapozhnikova; Olga Yu. Abakumova; Tatyana A. Tsvetkova; Igor Dmitrievich Zalevsky; S. E. Goncharov; Artashes V. Karmenyan; Gelii V. Ponomarev

doi:10.1117/12.413699

31 January 2001 Novel photosensitizers for prospective clinical usage and some of their properties

Andrei V. Reshetnickov, Stefan B. Spaniol, N. P. Neugodova, G. A. Sapozhnikova, Olga Yu. Abakumova, Tatyana A. Tsvetkova, Igor Dmitrievich Zalevsky, S. E. Goncharov, Artashes V. Karmenyan, Gelii V. Ponomarev

Author Affiliations +

Proceedings Volume 4156, Clinical Lasers and Diagnostics; (2001) https://doi.org/10.1117/12.413699
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

Five novel photosensitizers for photodynamic tumor therapy have been offered as potential drug substances for the prospective clinical usage. A complex of pre-clinic biological studies has been performed, unambiguously demonstrating low systemic toxicity and high photodynamic potential of the substances proposed. The one named 'Photodithazine/Photochlorin I' has already successfully passed a number of clinical test on patients having immergent vital indications.

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Andrei V. Reshetnickov, Stefan B. Spaniol, N. P. Neugodova, G. A. Sapozhnikova, Olga Yu. Abakumova, Tatyana A. Tsvetkova, Igor Dmitrievich Zalevsky, S. E. Goncharov, Artashes V. Karmenyan, and Gelii V. Ponomarev "Novel photosensitizers for prospective clinical usage and some of their properties", Proc. SPIE 4156, Clinical Lasers and Diagnostics, (31 January 2001); https://doi.org/10.1117/12.413699

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