NIR spectroscopy for the diagnosis of testicular pathologies

Eckhard Schleicher; Uwe Hampel; H. Zepnick; Richard Freyer

doi:10.1117/12.407627

22 November 2000 NIR spectroscopy for the diagnosis of testicular pathologies

Eckhard Schleicher, Uwe Hampel, H. Zepnick, Richard Freyer

Proceedings Volume 4160, Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography: Imaging and Functional Assessment; (2000) https://doi.org/10.1117/12.407627
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

NIR spectroscopy is a method principally capable of measuring tissue perfusion and oxygen saturation in subsurface and deeper tissue layers. In urology such perfusion related parameters are of some importance for the differentiation and evaluation of certain types of testicular pathologies. Among them are in the first place the differentiation between inflammations and torsion of the testis, both with similar symptoms, and the assessment of tissue viability in cases of torsion and necrosis, which is sometimes not sufficiently covered by sonography. Although NIR spectroscopy is the method of choice to measure blood oxygen saturation in tissue non- invasively the strong light scattering complicates spectroscopy quantification methods. Spatially-resolved spectroscopy (SRS) is one method to quantify absolute oxygen saturation and relative blood volume. To evaluate this method for in-vivo measurements we have developed a laser scanning device and evaluated quantification algorithms by help of numerical and experimental investigations. As first results suggest the method can in principle quantify absorption differences in tissue, oxygen saturation measurements, however, not work on the testis under the simplified assumptions made for other parts of the body.

Citation Download Citation

Eckhard Schleicher, Uwe Hampel, H. Zepnick, and Richard Freyer "NIR spectroscopy for the diagnosis of testicular pathologies", Proc. SPIE 4160, Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography: Imaging and Functional Assessment, (22 November 2000); https://doi.org/10.1117/12.407627

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