Development of a fiber-optic confocal microendoscope for clinical endoscopy

Andrew R. Rouse; Angelique Kano; Arthur F. Gmitro

doi:10.1117/12.465251

1 May 2002 Development of a fiber-optic confocal microendoscope for clinical endoscopy

Andrew R. Rouse, Angelique Kano, Arthur F. Gmitro

Proceedings Volume 4613, Optical Biopsy IV; (2002) https://doi.org/10.1117/12.465251
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

A confocal micro endoscope has been developed to examine cellular pathology during optical biopsy. The system employs a flexible fiber optic catheter coupled to a slit-scan confocal microscope to image tissue at remote locations in the body. The catheter of the confocal micro endoscope consists of a fiber-optic imaging bundle, a miniature objective, and a miniature focusing mechanism. The system has a lateral resolution of 1.8 micrometers and an axial resolution of 25 micrometers . The confocal micro endoscope can operate in a grayscale or multi-spectral imaging mode. Extensive work has been done to design a new miniature objective and focusing mechanism that will allow the catheter to be routed through the therapeutic channel of a clinical endoscope. We present the design for a miniature F/1 achromatic objective with nearly diffraction limited performance. The objective will be coupled to a pneumatic focusing mechanism to provide focus control to 200 micrometers below the surface of the tissue. The new catheter has an overall diameter of 3mm with a rigid tip of only 20mm in length.

Citation Download Citation

Andrew R. Rouse, Angelique Kano, and Arthur F. Gmitro "Development of a fiber-optic confocal microendoscope for clinical endoscopy", Proc. SPIE 4613, Optical Biopsy IV, (1 May 2002); https://doi.org/10.1117/12.465251

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