NIR time domain diffuse optical tomography experiments on human forearm

Huijuan Zhao; Feng Gao; Yukari Tanikawa; Kazuhiro Homma; Yukio Yamada

doi:10.1117/12.476557

29 July 2003 NIR time domain diffuse optical tomography experiments on human forearm

Huijuan Zhao, Feng Gao, Yukari Tanikawa, Kazuhiro Homma, Yukio Yamada

Proceedings Volume 4955, Optical Tomography and Spectroscopy of Tissue V; (2003) https://doi.org/10.1117/12.476557
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

To date, the applications of near infrared (NIR) diffusion optical tomography (DOT) are mostly focused on the potential of imaging woman breast, human head hemodynamics and neonatal head. For the neonates, who are suffered from ischaemia or hemorrhages in brain, bedside monitoring of the cerebral perfusion situation, e.g., the blood oxygen saturation and blood volume, is necessary for avoiding permanent injure. NIR DOT is on the promising tools because it is noninvasive, smaller in size, and moveable. Prior to achieving the ultimate goal of imaging infant brain and woman breast using DOT, in this paper, the developed methodologies are justified by imaging in vivo human forearms. The absolute absorption- and scattering-coefficient images revealed the inner structure of the forearm and the bones were clearly distinguished from the muscle. The differential images showed the changes in oxy-hemoglobin, deoxy-hemoglobin and blood volume during the hand-gripping exercises, which are consistent with the physiological process reported on literatures.

Citation Download Citation

Huijuan Zhao, Feng Gao, Yukari Tanikawa, Kazuhiro Homma, and Yukio Yamada "NIR time domain diffuse optical tomography experiments on human forearm", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); https://doi.org/10.1117/12.476557

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