Ocular scanning instrumentation: rapid diagnosis of chemical threat agent exposure

Lance R. Molnar; J. Vernon Odom; Bradley G. DeRoos; Christopher J. Kolanko

doi:10.1117/12.546589

15 September 2004 Ocular scanning instrumentation: rapid diagnosis of chemical threat agent exposure

Lance R. Molnar, J. Vernon Odom, Bradley G. DeRoos, Christopher J. Kolanko

Proceedings Volume 5403, Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Security and Homeland Defense III; (2004) https://doi.org/10.1117/12.546589
Event: Defense and Security, 2004, Orlando, Florida, United States

Abstract

Military personnel and first responders are in critical need of a sensitive technology for the rapid evaluation and diagnosis of exposure to adverse chemical agents. Ideally such a technology would be automated, easily portable, possess a high degree of sensitivity and specificity, and provide non-invasive assessment of health status. A potential method for meeting these requirements is via monitoring of ocular characteristics. Due to the interconnection between the eyes and the various physiological systems of the body, insults to the body may create a unique "thumbprint" upon the eyes based upon how these various physiological systems are differentially affected. In turn, these thumbprints (biomarkers) may be used to perform diagnostic evaluations of an individual’s health status. Based upon this principle, the Ocular Scanning Instrumentation (OSI) technology is being developed as an automated device for non-invasive monitoring of optically apparent characteristics and attributes of the eyes for in-the-field diagnosis of battlefield traumas, insults, and threat agent exposures. The current manuscript presents comparative data for two of the agents which we have evaluated, carbon monoxide and cyanide. The defined methods provide the required specificity and sensitivity needed for detecting exposures at time points which provide an ample therapeutic window for medical intervention.

Citation Download Citation

Lance R. Molnar, J. Vernon Odom, Bradley G. DeRoos, and Christopher J. Kolanko "Ocular scanning instrumentation: rapid diagnosis of chemical threat agent exposure", Proc. SPIE 5403, Sensors, and Command, Control, Communications, and Intelligence (C3I) Technologies for Homeland Security and Homeland Defense III, (15 September 2004); https://doi.org/10.1117/12.546589

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