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Time-resolved optical measurements allow for evaluation of optical properties of the tissue (in particular, absorption and reduced scattering coefficient). A four-channel time-resolved spectroscopic system for measurements of the tissue optical properties is presented. Four semiconductor diode lasers were used for emission of picosecond pulses at wavelengths of 633, 687, 784 and 832 nm. Optical fibers were applied to deliver the laser light into the tissue studied. The diffusely reflected light was transmitted to the photodetectors through fiber bundles. Four photomultiplier tubes were used for light detection and four independent time-correlated single photon counting boards were applied to obtain distributions of times of flight of photons. Measurements on liquid phantoms were carried out to test the temporal resolution and stability of the system and to demonstrate its usefulness in non-invasive determination of optical properties of the tissue.
Michal Kacprzak,A. Huzandrov,Adam Liebert, andRoman Maniewski
"Time-resolved spectroscopy system for determination of optical properties of the tissue: studies on physical phantoms", Proc. SPIE 5505, Optical Methods, Sensors, Image Processing, and Visualization in Medicine, (7 July 2004); https://doi.org/10.1117/12.577621
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Michal Kacprzak, A. Huzandrov, Adam Liebert, Roman Maniewski, "Time-resolved spectroscopy system for determination of optical properties of the tissue: studies on physical phantoms," Proc. SPIE 5505, Optical Methods, Sensors, Image Processing, and Visualization in Medicine, (7 July 2004); https://doi.org/10.1117/12.577621