Studying brain function with concurrent near-infrared spectroscopy (NIRS) and functional magnetic resonance imaging (fMRI)

A. Sassaroli; Y. Tong; B. B. Frederick; P. F. Renshaw; B. L. Ehrenberg; S. Fantini

doi:10.1117/12.588422

28 April 2005 Studying brain function with concurrent near-infrared spectroscopy (NIRS) and functional magnetic resonance imaging (fMRI)

A. Sassaroli, Y. Tong, B. B. Frederick, P. F. Renshaw, B. L. Ehrenberg, S. Fantini

Author Affiliations +

Proceedings Volume 5693, Optical Tomography and Spectroscopy of Tissue VI; (2005) https://doi.org/10.1117/12.588422
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

We present concurrent NIRS-fMRI measurements on a human subject during a finger tapping test. The optical data were collected with a frequency domain experimental apparatus (ISS, Inc., Champaign IL) comprising sixteen laser sources at 690 nm, sixteen laser sources at 830 nm and four photomultiplier tube detectors. The lasers were coupled to optical fibers that led the light onto the subject's head. A special optical helmet (fMRI-compatible) with a retractable and resilient set of optical fibers was devised to improve the coupling between the fibers and the scalp. The fMRI data were collected with a 3 Tesla Siemens Trio magnetic resonance scanner and a quadrature birdcage radiofrequency coil. The spatial and temporal comparison of the fMRI and NIRS signals associated with brain activation showed a very good agreement, confirming the role of NIRS as a reliable brain monitor for functional studies.

Citation Download Citation

A. Sassaroli, Y. Tong, B. B. Frederick, P. F. Renshaw, B. L. Ehrenberg, and S. Fantini "Studying brain function with concurrent near-infrared spectroscopy (NIRS) and functional magnetic resonance imaging (fMRI)", Proc. SPIE 5693, Optical Tomography and Spectroscopy of Tissue VI, (28 April 2005); https://doi.org/10.1117/12.588422

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available