Analysis of multiple scattering effects in optical Doppler tomography

Harold T. Yura; Lars Thrane; Peter Eskil Andersen

doi:10.1117/12.632969

7 October 2005 Analysis of multiple scattering effects in optical Doppler tomography

Harold T. Yura, Lars Thrane, Peter Eskil Andersen

Proceedings Volume 5861, Optical Coherence Tomography and Coherence Techniques II; 58610B (2005) https://doi.org/10.1117/12.632969
Event: European Conferences on Biomedical Optics 2005, 2005, Munich, Germany

Abstract

Optical Doppler tomography (ODT) combines Doppler velocimetry and optical coherence tomography (OCT) to obtain high-resolution cross-sectional imaging of particle flow velocity in scattering media such as the human retina and skin. Here, we present the results of a theoretical analysis of ODT where multiple scattering effects are included. The purpose of this analysis is to determine how multiple scattering affects the estimation of the depth-resolved localized flow velocity. Depth-resolved velocity estimates are obtained directly from the corresponding mean or standard deviation of the observed Doppler frequency spectrum. Thus, in the present analysis, the dependence of the mean and standard deviation of the Doppler shift on the scattering properties of the flowing medium are obtained. Taking the multiple scattering effects into account, we are able to explain previous measurements of depth-resolved retinal flow profiles where the influence of multiple scattering was observed [Yazdanfar et al., Opt. Lett. 25, 1448 (2000)]. To the best of our knowledge, no analytical model exists that are able to explain these observations.

Citation Download Citation

Harold T. Yura, Lars Thrane, and Peter Eskil Andersen "Analysis of multiple scattering effects in optical Doppler tomography", Proc. SPIE 5861, Optical Coherence Tomography and Coherence Techniques II, 58610B (7 October 2005); https://doi.org/10.1117/12.632969

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available