Adaptive optics/optical coherence tomography for in vivo retinal imaging: comparative analysis of two wavefront correctors

Robert J. Zawadzki; Steven M. Jones; Mingtao Zhao; Stacey S. Choi; Sophie S. Laut; Scot S. Olivier; Joseph A. Izatt; John S. Werner

doi:10.1117/12.647568

20 February 2006 Adaptive optics/optical coherence tomography for in vivo retinal imaging: comparative analysis of two wavefront correctors

Robert J. Zawadzki, Steven M. Jones, Mingtao Zhao, Stacey S. Choi, Sophie S. Laut, Scot S. Olivier, Joseph A. Izatt, John S. Werner

Author Affiliations +

Proceedings Volume 6079, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X; 607908 (2006) https://doi.org/10.1117/12.647568
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

Adaptive optics-optical coherence tomography (AO-OCT) has the potential to improve lateral resolution for OCT retinal imaging. Several reports have already described the successful combination of AO with a scanning confocal Fourier-domain OCT instrument to permit real-time three-dimensional (3D) imaging with high resolution (in all three dimensions). One of the key components that sets the performance limit of AO is the wavefront corrector. Several different wavefront correctors have been used in AO-OCT systems so far. In this paper we compare two commercially available wavefront correctors: an AOptix Bimorph deformable mirror (DM) and a Boston Micromachines Micro- Electro Mechanical System (MEMS) DM (used for the first time in an AO-OCT system). To simplify the analysis, we tested their performance for the correction of low-amplitude high-order aberrations (with minimal defocus and astigmatism). Results were obtained with an AO-OCT instrument constructed at UC Davis that combines state-of-the-art Fourier-domain OCT and an AO design to allow simultaneous testing of both mirrors without the need to modify the optical system.

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Robert J. Zawadzki, Steven M. Jones, Mingtao Zhao, Stacey S. Choi, Sophie S. Laut, Scot S. Olivier, Joseph A. Izatt, and John S. Werner "Adaptive optics/optical coherence tomography for in vivo retinal imaging: comparative analysis of two wavefront correctors", Proc. SPIE 6079, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X, 607908 (20 February 2006); https://doi.org/10.1117/12.647568

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