Time-resolved photon migration through an adult head model: comparison between Finite Element and Monte Carlo calculations

C. Mansouri; J. P. L'Huillier

doi:10.1117/12.728636

13 July 2007 Time-resolved photon migration through an adult head model: comparison between finite element and Monte Carlo calculations

C. Mansouri, J. P. L'Huillier

Author Affiliations +

Proceedings Volume 6632, Therapeutic Laser Applications and Laser-Tissue Interactions III; 66320L (2007) https://doi.org/10.1117/12.728636
Event: European Conferences on Biomedical Optics, 2007, Munich, Germany

Abstract

In this work, a Finite Element calculations based on diffusion approximation are compared with Monte Carlo transport data code in time-resolved reflectance simulations of light propagation in a three-layered head model, which can be seen as a very simplistic approximation of the adult head. We also address the effects caused by the cerebrospinal fluid (CSF), filling the space between the skull and the brain, on the accuracy of the diffusion approximation for different values of CSF reduced scattering coefficients μ_s' varying between 0.1 and 1 mm^-1. Significant differences between transport and diffusion calculations show that diffusion approximation fails to describe accurately light propagation in voidlike region such as the cerebrospinal fluid (CSF), in which absorption and scattering are very small compared to the surrounding media, whereas the Monte Carlo predictions are not greatly affected. However, It is shown that the diffusion equation should provide reasonable solutions with a CSF reduced scattering coefficient μ_s' = 0.3 mm^-1. The results indicate that a multi-layered model including CSF is more appropriate for the determination of the optical properties of the human head and to obtain accurate solutions of the forward problem with diffusion approximation.

Citation Download Citation

C. Mansouri and J. P. L'Huillier "Time-resolved photon migration through an adult head model: comparison between finite element and Monte Carlo calculations", Proc. SPIE 6632, Therapeutic Laser Applications and Laser-Tissue Interactions III, 66320L (13 July 2007); https://doi.org/10.1117/12.728636

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available