High-resolution PS-OCT of enamel remineralization

Anna M. Can; Cynthia L. Darling; Daniel Fried

doi:10.1117/12.778787

11 February 2008 High-resolution PS-OCT of enamel remineralization

Anna M. Can, Cynthia L. Darling, Daniel Fried

Proceedings Volume 6843, Lasers in Dentistry XIV; 68430T (2008) https://doi.org/10.1117/12.778787
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Previous studies have demonstrated that Polarization Sensitive Optical Coherence Tomography (PS-OCT) can be used to image the remineralization of early artificial caries lesions. However, the depth resolution of the imaging system employed in those previous studies was limited and the outer surface structure of the lesions were not resolved as clearly as desired. The purpose of this study was to repeat the earlier remineralization study using a broadband light-source of higher resolution to determine if there can be improved resolution of the remineralized surface zones of the lesions. An all polarization-maintaining fiber based PS-OCT system operating at 1310-nm was used to acquire polarization resolved images of bovine enamel surfaces exposed to a demineralizing solution at pH-4.9 followed by a fluoride containing remineralizing solution at pH-7.0 containing 2-ppm fluoride. The structure of surface zones could be clearly resolved in the samples that remineralized using PS-OCT. PS-OCT measured a significant (p<0.05) reduction in the integrated reflectivity between the severity of the lesions that were exposed to the remineralization solution and those that were not. The lesion depth and mineral loss was also measured with polarized light microscopy and transverse microradiography after sectioning the enamel blocks. These results show that PS-OCT can be used to non-destructively monitor the remineralization potential of anti-caries agents.

Citation Download Citation

Anna M. Can, Cynthia L. Darling, and Daniel Fried "High-resolution PS-OCT of enamel remineralization", Proc. SPIE 6843, Lasers in Dentistry XIV, 68430T (11 February 2008); https://doi.org/10.1117/12.778787

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