Quantification of carotid arteries atherosclerosis using 3D ultrasound images and area-preserving flattened maps

Bernard Chiu; Micaela Egger; J. David Spence; Grace Parraga; Aaron Fenster

doi:10.1117/12.770359

12 March 2008 Quantification of carotid arteries atherosclerosis using 3D ultrasound images and area-preserving flattened maps

Bernard Chiu, Micaela Egger, J. David Spence, Grace Parraga, Aaron Fenster

Author Affiliations +

Proceedings Volume 6916, Medical Imaging 2008: Physiology, Function, and Structure from Medical Images; 691603 (2008) https://doi.org/10.1117/12.770359
Event: Medical Imaging, 2008, San Diego, California, United States

Abstract

Quantitative measurements of the progression (or regression) of carotid plaque burden are important in monitoring patients and evaluating new treatment options. 3D ultrasound (US) has been used to monitor the progression of carotid artery plaques in symptomatic and asymptomatic patients. Different methods of measuring various ultrasound phenotypes of atherosclerosis have been developed. In this work, we extended concepts used in intima-media thickness (IMT) measurements based on 2D images and introduced a metric called 3D vessel-wall-plus-plaque thickness (3D VWT), which was obtained by computing the distance between the carotid wall and lumen surfaces on a point-by-point basis in a 3D image of the carotid arteries. The VWT measurements were then superimposed on the arterial wall to produce the VWT map. Since the progression of plaque thickness is important in monitoring patients who are at risk for stroke, we also computed the change of VWT by comparing the VWT maps obtained for a patient at two different time points. In order to facilitate the visualization and interpretation of the 3D VWT and VWT-Change maps, we proposed a technique to flatten these maps in an area-preserving manner.

Citation Download Citation

Bernard Chiu, Micaela Egger, J. David Spence, Grace Parraga, and Aaron Fenster "Quantification of carotid arteries atherosclerosis using 3D ultrasound images and area-preserving flattened maps", Proc. SPIE 6916, Medical Imaging 2008: Physiology, Function, and Structure from Medical Images, 691603 (12 March 2008); https://doi.org/10.1117/12.770359

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