Error analysis of tissue optical properties determined by double-integrating sphere system and inverse Monte Carlo method

Takaya Terada; Takuya Nanjo; Norihiro Honda; Katsunori Ishii; Kunio Awazu

doi:10.1117/12.876018

3 March 2011 Error analysis of tissue optical properties determined by double-integrating sphere system and inverse Monte Carlo method

Takaya Terada, Takuya Nanjo, Norihiro Honda, Katsunori Ishii, Kunio Awazu

Author Affiliations +

Proceedings Volume 7897, Optical Interactions with Tissue and Cells XXII; 78971W (2011) https://doi.org/10.1117/12.876018
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

To estimate the error of scattering coefficient spectrum determined by using double-integrating sphere system and inverse Monte Carlo method, optical properties of tissue phantom were measured. The tissue phantom was composed of hemoglobin, intralipid and gelatin. The thickness of samples (0.1-1.0 mm) and hemoglobin concentration (0.5-4.0 mg/ml) were changed and the effects of optical properties spectra were investigated. As the results, when the value of μa was large, μ's spectrum was not consistent with scattering theory. The higher hemoglobin concentration of samples was the lager the errors of μ's spectra were. The thinner the sample was, the smaller the errors were. However μa spectrum was not accurate when the sample was thin. It was predicted that when the sample thickness was 0.1 mm μ's spectrum was accurate. And when the sample thickness was 1.0 mm, μa spectrum was accurate.

Citation Download Citation

Takaya Terada, Takuya Nanjo, Norihiro Honda, Katsunori Ishii, and Kunio Awazu "Error analysis of tissue optical properties determined by double-integrating sphere system and inverse Monte Carlo method", Proc. SPIE 7897, Optical Interactions with Tissue and Cells XXII, 78971W (3 March 2011); https://doi.org/10.1117/12.876018

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