Temperature elevations in prostatic tumors during laser photothermal therapy

L. Zhu; A. Attaluri; H. Cai; R. Edziah; E. Lalanne; C. Bieberich; R. Ma; A. M. Johnson

doi:10.1117/12.882746

26 May 2011 Temperature elevations in prostatic tumors during laser photothermal therapy

L. Zhu, A. Attaluri, H. Cai, R. Edziah, E. Lalanne, C. Bieberich, R. Ma, A. M. Johnson

Proceedings Volume 8025, Smart Biomedical and Physiological Sensor Technology VIII; 80250G (2011) https://doi.org/10.1117/12.882746
Event: SPIE Defense, Security, and Sensing, 2011, Orlando, Florida, United States

Abstract

In vivo experiments were performed to measure temperature elevations in prostatic tumors implanted in mice during laser photothermal therapy using nanorods. Ti:Sapphire laser tuned at 800 nm irradiating the surface of the tumor delivered an average laser power of 0.5 - 1.0 W, equivalent to a laser radiance of 1.3-2.6 W/cm². The temperature elevations measured by two thermocouples located at the center and bottom of the tumor have shown non-uniform tumor temperature field, 10-30°C above the baseline temperature of 37°C. The experimental studies have demonstrated the capability of confining laser energy in tumors by a very small amount of nanorod solution.

Citation Download Citation

L. Zhu, A. Attaluri, H. Cai, R. Edziah, E. Lalanne, C. Bieberich, R. Ma, and A. M. Johnson "Temperature elevations in prostatic tumors during laser photothermal therapy", Proc. SPIE 8025, Smart Biomedical and Physiological Sensor Technology VIII, 80250G (26 May 2011); https://doi.org/10.1117/12.882746

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available