Two-photon absorbing chromophores for photodynamic therapy: molecular engineering and in vivo applications

Cyrille Monnereau; Thibault Gallavardin; Chloé Armagnat; Pierre-Henri Lanoé; Olivier Maury; Sophie Marotte; Yann Leverrier; Patrice L. Baldeck; Chantal Andraud

doi:10.1117/12.895984

15 September 2011 Two-photon absorbing chromophores for photodynamic therapy: molecular engineering and in vivo applications

Cyrille Monnereau, Thibault Gallavardin, Chloé Armagnat, Pierre-Henri Lanoé, Olivier Maury, Sophie Marotte, Yann Leverrier, Patrice L. Baldeck, Chantal Andraud

Author Affiliations +

Proceedings Volume 8103, Nanobiosystems: Processing, Characterization, and Applications IV; 81030N (2011) https://doi.org/10.1117/12.895984
Event: SPIE NanoScience + Engineering, 2011, San Diego, California, United States

Abstract

Recent examples of our works in the field of molecular engineering of chromophores for two-photon photodynamic therapy (PDT), and their vectorization into biological medium are presented and discussed. In a first section of this article, we show that a commercial amphiphilic diblock copolymer can be used as a micellar container for efficient delivery of s standard two-photon PDT sensitizer into cells. In a second section, we show how a simple molecular engineering strategy can be used to improve the performances of two-photon PDT sensitizer in the biological transparency-window.

Citation Download Citation

Cyrille Monnereau, Thibault Gallavardin, Chloé Armagnat, Pierre-Henri Lanoé, Olivier Maury, Sophie Marotte, Yann Leverrier, Patrice L. Baldeck, and Chantal Andraud "Two-photon absorbing chromophores for photodynamic therapy: molecular engineering and in vivo applications", Proc. SPIE 8103, Nanobiosystems: Processing, Characterization, and Applications IV, 81030N (15 September 2011); https://doi.org/10.1117/12.895984

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available