Measuring hemoglobin amount and oxygen saturation of skin with advancing age

Shumpei Watanabe; Satoshi Yamamoto; Midori Yamauchi; Norimichi Tsumura; Keiko Ogawa-Ochiai; Tetsuo Akiba

doi:10.1117/12.907874

2 February 2012 Measuring hemoglobin amount and oxygen saturation of skin with advancing age

Shumpei Watanabe, Satoshi Yamamoto, Midori Yamauchi, Norimichi Tsumura, Keiko Ogawa-Ochiai, Tetsuo Akiba

Proceedings Volume 8229, Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV; 822905 (2012) https://doi.org/10.1117/12.907874
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

We measured the oxygen saturation of skin at various ages using our previously proposed method that can rapidly simulate skin spectral reflectance with high accuracy. Oxygen saturation is commonly measured by a pulse oximeter to evaluate oxygen delivery for monitoring the functions of heart and lungs at a specific time. On the other hand, oxygen saturation of skin is expected to assess peripheral conditions. Our previously proposed method, the optical path-length matrix method (OPLM), is based on a Monte Carlo for multi-layered media (MCML), but can simulate skin spectral reflectance 27,000 times faster than MCML. In this study, we implemented an iterative simulation of OPLM with a nonlinear optimization technique such that this method can also be used for estimating hemoglobin concentration and oxygen saturation from the measured skin spectral reflectance. In the experiments, the skin reflectance spectra of 72 outpatients aged between 20 and 86 years were measured by a spectrophotometer. Three points were measured for each subject: the forearm, the thenar eminence, and the intermediate phalanx. The result showed that the oxygen saturation of skin remained constant at each point as the age varied.

Citation Download Citation

Shumpei Watanabe, Satoshi Yamamoto, Midori Yamauchi, Norimichi Tsumura, Keiko Ogawa-Ochiai, and Tetsuo Akiba "Measuring hemoglobin amount and oxygen saturation of skin with advancing age", Proc. SPIE 8229, Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV, 822905 (2 February 2012); https://doi.org/10.1117/12.907874

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