2D photoacoustic scanning imaging with a single pulsed laser diode excitation

Xuegang Chen; Changwei Li; Lvming Zeng; Guodong Liu; Zhen Huang; Zhong Ren

doi:10.1117/12.918741

13 March 2012 2D photoacoustic scanning imaging with a single pulsed laser diode excitation

Xuegang Chen, Changwei Li, Lvming Zeng, Guodong Liu, Zhen Huang, Zhong Ren

Proceedings Volume 8329, Tenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011); 832909 (2012) https://doi.org/10.1117/12.918741
Event: Photonics and Optoelectronics Meetings 2011, 2011, Wuhan, China

Abstract

A portable near-infrared photoacoustic scanning imaging system has been developed with a single pulsed laser diode, which was integrated with an optical lens system to straightforward boost the laser energy density for photoacoustic generation. The 905 nm laser diode provides a maximum energy output of 14 μJ within 100 ns pulse duration, and the pulse repetition frequency rate is 0.8 KHz. As a possible alternative light source, the preliminary 2D photoacoustic results primely correspond with the test phantoms of umbonate extravasated gore and knotted blood vessel network. The photoacoustic SNR can reach 20.6±1.2 dB while signal averaging reduces to 128 pulses from thousands to tens of thousands times, and the signal acquisition time accelerates to less than 0.2 s in each A-scan, especially the volume of the total radiation source is only 10 × 3 × 3 cm³. It demonstrated that the pulsed semiconductor laser could be a candidate of photoacoustic equipment for daily clinical application.

Citation Download Citation

Xuegang Chen, Changwei Li, Lvming Zeng, Guodong Liu, Zhen Huang, and Zhong Ren "2D photoacoustic scanning imaging with a single pulsed laser diode excitation", Proc. SPIE 8329, Tenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011), 832909 (13 March 2012); https://doi.org/10.1117/12.918741

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