Photoacoustic viscoelasticity detection of biological tissues with phase-resolved method

Yue Zhao; Sihua Yang

doi:10.1117/12.918831

13 March 2012 Photoacoustic viscoelasticity detection of biological tissues with phase-resolved method

Yue Zhao, Sihua Yang

Proceedings Volume 8329, Tenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011); 83290E (2012) https://doi.org/10.1117/12.918831
Event: Photonics and Optoelectronics Meetings 2011, 2011, Wuhan, China

Abstract

A method for noninvasive viscoelasticity detection of biological tissues using phase-resolved photoacoustic measurement is presented. We deduced the process of photoacoustic effect on the basis of thermal viscoelasticity theory, and established the relationship between the photoacoustic phase delay and the viscosity-elasticity ratio for soft solids. Agar phantoms with different densities and different absorption coefficients were used to verify the dependence of photoacoustic phase-resolved viscoelasticity measurement. Moreover, viscoelasticity detection of tissues was obtained with a photoacoustic point scanning system. The photoacoustic phase-resolved method provides a basis for viscoelasticity detection, which can potentially be used for detection of viscoelastic properties and lesions of biological tissues.

Citation Download Citation

Yue Zhao and Sihua Yang "Photoacoustic viscoelasticity detection of biological tissues with phase-resolved method", Proc. SPIE 8329, Tenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011), 83290E (13 March 2012); https://doi.org/10.1117/12.918831

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KEYWORDS

Tissues

Photoacoustic spectroscopy

Modulation

Phase measurement

Absorption

Phase shift keying

Solids

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