Investigation of magnetic field enriched surface-enhanced resonance Raman scattering performance using Fe3O4@Ag nanoparticles for malaria diagnosis

Clement Yuen; Quan Liu

doi:10.1117/12.2038870

24 March 2014 Investigation of magnetic field enriched surface enhanced resonance Raman scattering performance using Fe₃O₄@Ag nanoparticles for malaria diagnosis

Clement Yuen, Quan Liu

Author Affiliations +

Proceedings Volume 8955, Colloidal Nanoparticles for Biomedical Applications IX; 895516 (2014) https://doi.org/10.1117/12.2038870
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Recently, we have demonstrated the magnetic field-enriched surface-enhanced resonance Raman spectroscopy (SERRS) of β-hematin by using nanoparticles with iron oxide core and silver shell (Fe₃O₄@Ag) for the potential application in the early malaria diagnosis. In this study, we investigate the dependence of the magnetic field-enriched SERRS performance of β-hematin on the different core and shell sizes of the Fe₃O₄@Ag nanoparticles. We note that the core and shell parameters are critical in the realization of the optimal magnetic field-enrich SERRS β-hematin signal. These results are consistent with our simulations that will guide the optimization of the magnetic SERRS performance for the potential early diagnosis in the malaria disease.

Citation Download Citation

Clement Yuen and Quan Liu "Investigation of magnetic field enriched surface enhanced resonance Raman scattering performance using Fe₃O₄@Ag nanoparticles for malaria diagnosis", Proc. SPIE 8955, Colloidal Nanoparticles for Biomedical Applications IX, 895516 (24 March 2014); https://doi.org/10.1117/12.2038870

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