Raman spectroscopy for monitoring of organic and mineral structure of bone grafts

Elena V. Timchenko; Pavel E. Timchenko; Larisa T. Volova; Julia V. Ponomareva; Larisa A. Taskina; Svetlana V. Pershutkina

doi:10.1117/12.2062282

5 September 2014 Raman spectroscopy for monitoring of organic and mineral structure of bone grafts

Elena V. Timchenko, Pavel E. Timchenko, Larisa T. Volova, Julia V. Ponomareva, Larisa A. Taskina, Svetlana V. Pershutkina

Author Affiliations +

Proceedings Volume 9198, Ultrafast Nonlinear Imaging and Spectroscopy II; 919817 (2014) https://doi.org/10.1117/12.2062282
Event: SPIE Optical Engineering + Applications, 2014, San Diego, California, United States

Abstract

The results of experimental studies of donor bone samples (rat, rabbit and human) with varying degrees of mineralisation by Raman spectroscopy were presented. Raman spectra were obtained for the Raman bands 950-962 (РО₄)^3-, 1065-1070 (СО₃)^2- and 1665 cm-1 (Amide I). In demineralized bone a sharp decline (to 98 %) in the range of 950-962 cm-1 (РО₄)^3- and 1065 - 1070 cm^-1was observed. This decrease was accompanied by the emergence of the 1079-1090 cm-1 band corresponding to the hydrated state СО₃ ^2-.

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Elena V. Timchenko, Pavel E. Timchenko, Larisa T. Volova, Julia V. Ponomareva, Larisa A. Taskina, and Svetlana V. Pershutkina "Raman spectroscopy for monitoring of organic and mineral structure of bone grafts", Proc. SPIE 9198, Ultrafast Nonlinear Imaging and Spectroscopy II, 919817 (5 September 2014); https://doi.org/10.1117/12.2062282

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