High-speed quantitative interferometric microscopy based phase imaging cytometer

Liang Xue; Nan Sun; Keding Yan; Fei Liu; Shouyu Wang

doi:10.1117/12.2070398

18 November 2014 High-speed quantitative interferometric microscopy based phase imaging cytometer

Liang Xue, Nan Sun, Keding Yan, Fei Liu, Shouyu Wang

Proceedings Volume 9268, Optics in Health Care and Biomedical Optics VI; 926818 (2014) https://doi.org/10.1117/12.2070398
Event: SPIE/COS Photonics Asia, 2014, Beijing, China

Abstract

The paper proposed a simple large scale bio-sample phase detecting equipment called gravity driven phase detecting cytometer, which is based on quantitative interferometric microscopy to realize flowing red blood cells phase distribution detection. The method has advantages on high throughput phase detecting and statistical analysis with high detecting speed and in real-time. The statistical characteristics of red blood cells are useful for biological analysis and disease detection. We believe this method is shedding more light on quantitatively measurement of the phase distribution of bio-samples.

Citation Download Citation

Liang Xue, Nan Sun, Keding Yan, Fei Liu, and Shouyu Wang "High-speed quantitative interferometric microscopy based phase imaging cytometer", Proc. SPIE 9268, Optics in Health Care and Biomedical Optics VI, 926818 (18 November 2014); https://doi.org/10.1117/12.2070398

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KEYWORDS

Microscopy

Interferometry

Blood

Statistical analysis

Phase imaging

Phase measurement

Biological research

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