Optical wavefront shaping for the enhancement of Raman signal in scattering media

Jonathan V. Thompson; Graham A. Throckmorton; Brett H. Hokr; Vladislav V. Yakovlev

doi:10.1117/12.2213625

15 March 2016 Optical wavefront shaping for the enhancement of Raman signal in scattering media

Jonathan V. Thompson, Graham A. Throckmorton, Brett H. Hokr, Vladislav V. Yakovlev

Proceedings Volume 9717, Adaptive Optics and Wavefront Control for Biological Systems II; 97170M (2016) https://doi.org/10.1117/12.2213625
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

The ability to non-invasively focus light through scattering media has significant applications in many fields ranging from nanotechnology to deep tissue sensing. Until recently, the multiple light scattering events that occur in complex media such as biological tissue have inhibited the focusing ability and penetration depth of optical tools. Through the use of optical wavefront shaping, the spatial distortions due to these scattering events can be corrected, and the incident light can be focused through the scattering medium. Here, we demonstrate that wavefront shaping can be used to non-invasively enhance the Raman signal of a material through a scattering medium. Raman signal enhancement was achieved using backscattered light and a continuous sequential algorithm. Our results show the potential of wavefront shaping as an important addition to non-invasive detection techniques.

Conference Presentation

Citation Download Citation

Jonathan V. Thompson, Graham A. Throckmorton, Brett H. Hokr, and Vladislav V. Yakovlev "Optical wavefront shaping for the enhancement of Raman signal in scattering media", Proc. SPIE 9717, Adaptive Optics and Wavefront Control for Biological Systems II, 97170M (15 March 2016); https://doi.org/10.1117/12.2213625

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