Multispectral Stokes polarimetry for dermatoscopic imaging

Y. Castillejos; Geminiano Martínez-Ponce; Azael Mora-Nuñez; R. Castro-Sanchez

doi:10.1117/12.2205123

15 December 2015 Multispectral Stokes polarimetry for dermatoscopic imaging

Y. Castillejos, Geminiano Martínez-Ponce, Azael Mora-Nuñez, R. Castro-Sanchez

Proceedings Volume 9792, Biophotonics Japan 2015; 97921P (2015) https://doi.org/10.1117/12.2205123
Event: SPIE/OSJ Biophotonics Japan, 2015, Tokyo, Japan

Abstract

Most of skin pathologies, including melanoma and basal/squamous cell carcinoma, are related to alterations in external and internal order. Usually, physicians rely on their empirical expertise to diagnose these ills normally assisted with dermatoscopes. When there exists skin cancer suspicion, a cytology or biopsy is made, but both laboratory tests imply an invasive procedure. In this regard, a number of non-invasive optical techniques have been proposed recently to improve the diagnostic certainty and assist in the early detection of cutaneous cancer. Herein, skin optical properties are derived with a multispectral polarimetric dermatoscope using three different illumination wavelength intervals centered at 470, 530 and 635nm. The optical device consist of two polarizing elements, a quarter-wave plate and a linear polarizer, rotating at a different angular velocity and a CCD array as the photoreceiver. The modulated signal provided by a single pixel in the acquired image sequence is analyzed with the aim of computing the Stokes parameters. Changes in polarization state of selected wavelengths provide information about the presence of skin pigments such as melanin and hemoglobin species as well as collagen structure, among other components. These skin attributes determine the local physiology or pathology. From the results, it is concluded that optical polarimetry will provide additional elements to dermatologists in their diagnostic task.

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Y. Castillejos, Geminiano Martínez-Ponce, Azael Mora-Nuñez, and R. Castro-Sanchez "Multispectral Stokes polarimetry for dermatoscopic imaging", Proc. SPIE 9792, Biophotonics Japan 2015, 97921P (15 December 2015); https://doi.org/10.1117/12.2205123

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KEYWORDS

Polarimetry

Skin

Polarization

Diagnostics

Optical components

Linear polarizers

Tissue optics

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