Modeling study of terminal transients of blood flow

Elena S. Stiukhina; Dmitry E. Postnov

doi:10.1117/12.2229853

21 April 2016 Modeling study of terminal transients of blood flow

Proceedings Volume 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS); 991727 (2016) https://doi.org/10.1117/12.2229853
Event: Saratov Fall Meeting 2015, 2015, Saratov, Russian Federation

Abstract

In spite of growing body of experimental and theoretical results on blood flow (BF) patterns under the continuously sustained circulation, much less is known about BF dynamics under the exceptional, but still important cases of venous or arterial occlusion used in medical probes. Since these conditions finally lead to complete or nearly complete stop of red blood cells (RBC) motion, we term it as TTBF, being the Terminal Transients of Blood Flow. An extreme case of such transients is the ultimate extinction of BF after the stopping of heart contractions, during which it is governed by gravitation, some vascular-originated propulsion mechanisms, and, possibly, by RBC aggregation. Quite little is known about this process, while reports the detectable post-mortal motion of mice RBC during at least 2 hours. In our work we present the modeling study of TTBF patterns due to gravitational forces. We present the minimalistic model configuration of vasculature in order to simulate what happens immediately after the pumping of blood has been stopped. Our main findings are concerned to reversal of arterial BF, as well as to duration and non-monotonicity of transients.

Citation Download Citation

Elena S. Stiukhina and Dmitry E. Postnov "Modeling study of terminal transients of blood flow", Proc. SPIE 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS), 991727 (21 April 2016); https://doi.org/10.1117/12.2229853

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