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Blue light cystoscopy (BLC) has been demonstrated to detect bladder tumors with better sensitivity than white light cystoscopy (WLC); however, the use of BLC is limited to the operating room. In this study, we aim to bring BLC to the clinic by transforming WLC frames into digitally-stained BLC-like frames. We collected region-matched WLC and BLC videos from TURBT procedures and generated BLC-like frames, using WLC frames as input and the matched BLC frames as target. We will discuss the staining performances with perfectly registered WLC-BLC datasets, as well as WLC and BLC video clips collected with commercial clinical systems.
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Shuang Chang, Ali Abbasi, Kristen Scarpato, Amy Luckenbaugh, Sam Chang, Soheil Kolouri, Audrey K. Bowden, "Bringing blue light cystoscopy to the office: digital staining on matched white and blue light cystoscopy videos," Proc. SPIE PC12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI, PC123680P (6 March 2023); https://doi.org/10.1117/12.2649276