Characterizing retinal microcirculation heterogeneity in glaucoma using optical coherence tomography angiography

Tiffany Tse; Ansel Chen; Hoyoung Jung; Myeong Jin Ju; Yudan Chen; Zaid Mammo

doi:10.1117/12.3005363

13 March 2024 Characterizing retinal microcirculation heterogeneity in glaucoma using optical coherence tomography angiography

Tiffany Tse, Ansel Chen, Hoyoung Jung, Myeong Jin Ju, Yudan Chen, Zaid Mammo

Author Affiliations +

Proceedings Volume PC12824, Ophthalmic Technologies XXXIV; PC1282407 (2024) https://doi.org/10.1117/12.3005363
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Structural and functional dysregulation of the retinal microvasculature have been implicated in the pathogenesis of glaucomatous optic neuropathy. To detect relative blood perfusion heterogeneity in the macular circulation in subjects with glaucoma and healthy controls, we used a commercial optical coherence tomography angiography (OCTA) system with a custom post-acquisition image processing software, involving multi-volume registration and averaging. In 10 subjects diagnosed with glaucoma and 5 control subjects, we observed differences among patient groups in retinal vasculature perfusion heterogeneity, as a potential marker for vascular dysregulation.

Conference Presentation

Citation Download Citation

Tiffany Tse, Ansel Chen, Hoyoung Jung, Myeong Jin Ju, Yudan Chen, and Zaid Mammo "Characterizing retinal microcirculation heterogeneity in glaucoma using optical coherence tomography angiography", Proc. SPIE PC12824, Ophthalmic Technologies XXXIV, PC1282407 (13 March 2024); https://doi.org/10.1117/12.3005363

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available