A 256-channel SPAD detector for time-gated fNIRS and DCS

Jonathan M. Richardson; Tom Y. Cheng; George Jordy; Matthew S. Stamplis; Ana-Maria Mandrila Vaca; Michael Bradshaw; Erik K. Duerr; Marco Renna; Mitchell B. Robinson; Stefan A. Carp; Maria-Angela Franceschini

doi:10.1117/12.3003159

13 March 2024 A 256-channel SPAD detector for time-gated fNIRS and DCS

Jonathan M. Richardson, Tom Y. Cheng, George Jordy, Matthew S. Stamplis, Ana-Maria Mandrila Vaca, Michael Bradshaw, Erik K. Duerr, Marco Renna, Mitchell B. Robinson, Stefan A. Carp, Maria-Angela Franceschini

Author Affiliations +

Proceedings Volume PC12828, Neural Imaging and Sensing 2024; PC128280E (2024) https://doi.org/10.1117/12.3003159
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Functional near-infrared spectroscopy (fNIRS) and diffuse correlation spectroscopy (DCS) have shown promise as non-invasive optical methods for cerebral functional imaging. Both approaches currently have limits to sensitivity in adults. Sensitivity can be improved using temporal discrimination, where the laser excitation is of short (~400ps) duration and the detector rejects early photons that have not penetrated into the brain while maintain high sensitivity to those that have. We report here further demonstration of a high-speed Read-Out Integrated Circuit (ROIC) that integrates with a 32x32 Single-Photon Avalanche photo-Detector (SPAD) array that can be either silicon (Si, for visible to infra-red) in indium-phosphide (InP, to allow operation at 1064nm). Data is exfiltrated serially directly to an FPGA where it can be processed in real time. This presentation will include results of recent detector performance tests and phantom demonstrations using this powerful new tool.

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(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

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Jonathan M. Richardson, Tom Y. Cheng, George Jordy, Matthew S. Stamplis, Ana-Maria Mandrila Vaca, Michael Bradshaw, Erik K. Duerr, Marco Renna, Mitchell B. Robinson, Stefan A. Carp, and Maria-Angela Franceschini "A 256-channel SPAD detector for time-gated fNIRS and DCS", Proc. SPIE PC12828, Neural Imaging and Sensing 2024, PC128280E (13 March 2024); https://doi.org/10.1117/12.3003159

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KEYWORDS

Readout integrated circuits

Near infrared spectroscopy

Silicon

Brain

Field programmable gate arrays

Functional imaging

Imaging spectroscopy

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