Full thickness retinal AO-OCT imaging with computational aberration correction

Dawid Borycki; Liu Zhuolin; Daniel X. Hammer; Maciej Wojtkowski

doi:10.1117/12.3003993

13 March 2024 Full thickness retinal AO-OCT imaging with computational aberration correction

Dawid Borycki, Liu Zhuolin, Daniel X. Hammer, Maciej Wojtkowski

Proceedings Volume PC12824, Ophthalmic Technologies XXXIV; PC128240Z (2024) https://doi.org/10.1117/12.3003993
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Adaptive optics optical coherence tomography (AO-OCT) provides state-of-the-art volumetric cellular-level imaging of the human retina in vivo. However, when coupled to AO, the OCT system's high transverse resolution reduces the depth of focus. A proven approach to this problem is acquiring AO-OCT volumes with the system focus set on different retinal layers and stitching the resulting volumes together. We demonstrate that this approach can be simplified using computational aberration correction (CAC). CAC enables us to correct AO-OCT volumes computationally in post-processing. So, we achieved an extended depth of focus without acquiring multiple AO-OCT volumes under the variable system focus settings.

Conference Presentation

Citation Download Citation

Dawid Borycki, Liu Zhuolin, Daniel X. Hammer, and Maciej Wojtkowski "Full thickness retinal AO-OCT imaging with computational aberration correction", Proc. SPIE PC12824, Ophthalmic Technologies XXXIV, PC128240Z (13 March 2024); https://doi.org/10.1117/12.3003993

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