Evaluation of changes in birefringence for samples subjected to various stress sources measured with polarization-sensitive OCT

Karol Karnowski; Qingyun Li; Martin Villiger; David D. Sampson

doi:10.1117/12.2270131

29 April 2017 Evaluation of changes in birefringence for samples subjected to various stress sources measured with polarization-sensitive OCT

Karol Karnowski, Qingyun Li, Martin Villiger, David D. Sampson

Author Affiliations +

Proceedings Volume 10340, International Conference on Biophotonics V; 1034016 (2017) https://doi.org/10.1117/12.2270131
Event: International Conference on Biophotonics V, 2017, Perth, Australia

Abstract

Polarization-sensitive OCT (PS-OCT) has proven useful in determining the stress-induced birefringence of non-biological materials, but such utility in biological tissues subjected to stress has not been well studied yet. To study stress-induced birefringence of biological tissues, we use a swept-source PS-OCT system with passively depth-encoded, orthogonal polarization states in the illumination path and polarization-diversity detection and a Mueller formalism in post-processing. We present measurements of stress-induced changes in the birefringence of non-biological and biological samples that provide useful benchmarks in further assessing the utility of this approach.

Citation Download Citation

Karol Karnowski, Qingyun Li, Martin Villiger, and David D. Sampson "Evaluation of changes in birefringence for samples subjected to various stress sources measured with polarization-sensitive OCT", Proc. SPIE 10340, International Conference on Biophotonics V, 1034016 (29 April 2017); https://doi.org/10.1117/12.2270131

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