Few-mode fiber detection for tissue characterization in optical coherence tomography

Pablo Eugui; Antonia Lichtenegger; Marco Augustin; Danielle J. Harper; Stanislava Fialová; Andreas Wartak; Christoph K. Hitzenberger; Bernhard Baumann

doi:10.1117/12.2287667

1 August 2017 Few-mode fiber detection for tissue characterization in optical coherence tomography

Pablo Eugui , Antonia Lichtenegger, Marco Augustin, Danielle J. Harper, Stanislava Fialová, Andreas Wartak, Christoph K. Hitzenberger, Bernhard Baumann

Author Affiliations +

Proceedings Volume 10416, Optical Coherence Imaging Techniques and Imaging in Scattering Media II; 104160M (2017) https://doi.org/10.1117/12.2287667
Event: European Conferences on Biomedical Optics, 2017, Munich, Germany

Abstract

A few-mode fiber based detection for OCT systems is presented. The capability of few-mode fibers for delivering light through different fiber paths enables the application of these fibers for angular scattering tissue character- ization. Since the optical path lengths traveled in the fiber change between the fiber modes, the OCT image information will be reconstructed at different depth positions, separating the directly backscattered light from the light scattered at other angles. Using the proposed method, the relation between the angle of reflection from the sample and the respective modal intensity distribution was investigated. The system was demonstrated for imaging ex-vivo brain tissue samples of patients with Alzheimer’s disease.

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Pablo Eugui , Antonia Lichtenegger, Marco Augustin, Danielle J. Harper, Stanislava Fialová, Andreas Wartak, Christoph K. Hitzenberger, and Bernhard Baumann "Few-mode fiber detection for tissue characterization in optical coherence tomography", Proc. SPIE 10416, Optical Coherence Imaging Techniques and Imaging in Scattering Media II, 104160M (1 August 2017); https://doi.org/10.1117/12.2287667

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