Examining phase contrast sensitivity to signal location and tissue thickness in breast imaging

Stefano Vespucci; Cale Lewis; Chan Soo Park; Mini Das

doi:10.1117/12.2294968

9 March 2018 Examining phase contrast sensitivity to signal location and tissue thickness in breast imaging

Stefano Vespucci, Cale Lewis, Chan Soo Park, Mini Das

Proceedings Volume 10573, Medical Imaging 2018: Physics of Medical Imaging; 1057324 (2018) https://doi.org/10.1117/12.2294968
Event: SPIE Medical Imaging, 2018, Houston, Texas, United States

Abstract

X-Ray phase contrast imaging (PCI) is being developed as an alternative to overcome the poor contrast sensitivity of existing attenuation imaging techniques. The “phase sensitivity” can be achieved using a number of phase-enhancing geometries such as free space propagation, grating interferometry and edge illumination (also known as coded aperture) technique. The enhanced contrast in the projected intensities (that combine absorption and phase effect) can vary by object shape, size and its material properties as well as the particular PCI method used. We show a comparison of this signal enhancement for both FSP and coded aperture (CA) PCI. Our data shows that the phase enhancement is significantly higher for CA in comparison to FSP. Our preliminary results indicate that the enhanced phase effect decreases in all PCI techniques with increasing background thickness. Investigations involving signal location and background tissue thickness dependent signal enhancement (and/or loss of this signal) are very important in determining the true benefit of PCI methods in a practical application involving thick organs like breast imaging.

Conference Presentation

Citation Download Citation

Stefano Vespucci, Cale Lewis, Chan Soo Park, and Mini Das "Examining phase contrast sensitivity to signal location and tissue thickness in breast imaging", Proc. SPIE 10573, Medical Imaging 2018: Physics of Medical Imaging, 1057324 (9 March 2018); https://doi.org/10.1117/12.2294968

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available